SDV2: Cryo-methods 1 : nano-objects

Yaser Hashem
ARNA, Pessac

Marc Schmutz
Institut Charles Sadron, Strasbourg
This symposium aims to provide an overview of new advances in methods for the preparation and analysis of cryo-TEM data, and of course, the contributions this makes to the quality of structures obtained at the atomic scale. For this purpose we want to bring together both developers and users of state-of-the-art Artificial Intelligence methods for image analysis, different methods of 3D structure determination and molecular modelling as well as fitting in cryo-EM reconstructions. We will focus not only on large macromolecular complexes, but also on small molecules of all kinds (nucleic acids, proteins and hybrids).
Keywords: cryo TEM, atomic scale structures, artificial intelligence, image analysis, 3D structures, molecular modelling.
Invited speakers

Thorsten Wagner
Max Planck Institüt of Molecular Physiology, Dortmund, Germany
Generalized 3D localization of macromolecules in cryo-electron tomograms with TomoTwin

Slavica Jonic
IMPMC-CNRS UMR 7590, Sorbonne université
Data analysis methods based on molecular dynamics simulation for studying continuous conformational variability